Xue Hongfan

Master’s Degree in Marine Biology, specializing in Molecular Biology.

During graduate studies, research focused on transcriptome and expression profile analysis of macroalgae, including bioinformatics software-based analysis of transcriptome and expression profile data, and molecular biology techniques for the identification of macroalgae.Authored 2 granted patents during university studies:

• A Fermenter Equipped with a Liquid Conveying Chamber and Its Application Method
• A Liquid Fermentation Method of Fungi and a Fermenter

These laid a solid foundation for a career in intellectual property as a patent attorney.Has been engaged in the intellectual property industry for nearly 10 years, working as a patent attorney.

Published two academic papers during IP practice:

1. A Brief Discussion on the Inventiveness Determination of Traditional Chinese Medicine Composition Patents in the Examination Process
2. Case Analysis and Response Strategies for Illegal Applications in Traditional Chinese Medicine Patent Filings

Proficient in handling new patent application drafting, office action responses, requests for re-examination, invalidation requests, responses to invalidation, and submission of public opinions in the fields of biology and chemistry.

Major Technical Fields

Molecular biology, bioinformatics, biomedicines, preparation and application of traditional Chinese and Western medicines, disease diagnosis, microbiology, immunology, genetic engineering, genetic breeding, in vitro diagnostic reagents, cell culture, plant tissue culture, separation, identification and application of plant active substances, agricultural disease control, organic synthesis, polymers, nanomaterials, etc.

Selected Representative Cases

Pharmaceuticals

• Drafted the patent case for Screening Method for Serum Differential Proteins in Rat Model of Abnormal Phlegm Type Impotence in Uyghur Medicine.

Disease Detection

• Drafted the patent case for A Kit for Detecting Gastric Cancer Based on RT-qPCR, Its Preparation Method and Application (for Jiansheng Biotechnology Co., Ltd.).

Molecular Biology & Genetic Engineering

• Drafted the patent case for A Genetically Engineered Protein with Immunoregulatory Negative Effect, Its Preparation Method and Application (for Fudan University).

Macromolecular Compounds

• Drafted the patent case for Application of F-STn-Based Glycoconjugates in Antitumor Vaccines (for Peking University).

Molecular Biology

• Drafted the patent case for Nanobody of Clostridium difficile Glutamate Dehydrogenase, Coding Sequence, Screening Method and Application Thereof.

Plant Tissue Culture

• Drafted the patent case for Establishment of Transgenic System for Effective Roots of Cajanus cajan and Its Economic Plants.

Virology

• Drafted the patent case for A Mutant Strain of Foot-and-Mouth Disease Virus Serotype O and Its Preparation Method and Application (for Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences).

Microbes & Functional Applications

• Drafted the patent case for A Strain Producing Penicillic Acid and Its Application.

Biofuel Cells

• Drafted the patent case for Method for Producing Bacterial Cellulose Membrane Using Corn Stover and Corn Stover Degradant Fuel Cell.

Protein Science

• Drafted the patent case for A Truncated Mutant of Non-Structural Protein NS1 of Japanese Encephalitis Virus, Its Encoding Gene and Application.

Pathogen Detection

• Drafted the patent case for Typing Method for Vibrio parahaemolyticus Based on Real-Time Fluorescent PCR (for Jiaxing Center for Disease Control and Prevention).

Environmental Detection

• Drafted the patent case for A Method for Detecting Microplastic Density Distribution in Marine Organism Soft Tissues.

Fermentation

• Drafted the patent case for A Koumiss Starter Culture and Its Preparation Method and Application.

Bioinformatics

• Drafted the patent case for An Automatic and Rapid Method for Analyzing Proteogenomics Data (for Institute of Hydrobiology, Chinese Academy of Sciences).
• Drafted the patent case for A Method for Screening miRNA Markers of Tumors Based on Multilayer Complex Networks.
• Drafted the patent case for A Construction Method of Photosynthetic Pathway Gene Regulatory Network.
• Drafted the patent case for Prediction of Phenotypic Traits and DNA Methylation Analysis in Populus simonii.

Working Languages

Chinese, English